COSMETICS & FILLER

MILANO

MADE IN ITALY

DERMAL FILLER SOFT

DERMAL FILLER MEDIUM

DERMAL FILLER STRONG

DERMAL FILLER EXTRA STRONG

BODY FILLER

BIOREVITALIZE

HYALURONIC ACID

It is an important component of articular cartilage as it responsible for its resilience (resistance to compression) where it is present as a coat around each cell. It is also a major component of epidermis and derma, where it is involved in tissue protection, resistance and repair. When the skin is exposed to excessive UVB rays, smoke, pollution and in the natural ageing process, the cells in the skin stops producing as much hyaluronan and, specially with the ageing, it increase the rate of its degradation. Therefore, we can assume that hyaluronic acid is well suited to biomedical applications on the cartilage, derma and epidermis with optimal results, biocompatible material, fast and comfortable procedure, save and non permanent effect.

CROSS-LINKING

The linear hyaluronic acid has a relatively short life after injection into the body. Special manufacturing techniques have been developed to extend the length of the hyaluronic acid chain and stabilise the molecule for longer results after the medical applications.
So, it was created a chemical procedure that introduced a protein into the solution creating the well known cross-linking hyaluronic acid.
The degradation of the hyaluronic acid became much slower and the results obtained once injected was definitely longer comparing with the linear type.

New life to the skin!

The cross-linked hyaluronic acid combines with thousand of water molecules expanding, where it is injected, the skin depressions, wrinkles and scars. At the same time, it hydrates the cells around the application and gives a shine and healthy appearance for the patient.
THJAMA' Filler counts with the cross linking technology, which grants a superior performance of the hyaluronic acid after its injection: longevity and moisture retention.

FLUIDITY

Another important characteristic of THJAMA' Filler is the product fluidity. Different from several companies, which the product injection is hard due to the high viscosity, the injection of THJAMA' Filler is smooth and comfortable. The personalized syringe with unique piston shape, gives a great grip, security and easy handling for the operator and, in consequence, a comfortable procedure for the patient. It is also very important to mention the great plastic feature of THJAMA' Filler when it is on-site as it can be mouldable by the doctors with the standard post procedure massage as it takes the desired shape and remains at the site.

FORMULATION

Specially created and developed in one of the most modern laboratory and research center by a highly qualified team, THJAMA' Filler uses a very save and secure cross-linking protocol where residuals of impurities are practically absent. All the production stages are made in a sterile environment (sterile chamber) which guarantees a pure final product
THJAMA' Fillercomposition counts with a specially selected HA molecular weight particles in different viscosities solution and different hyaluronic acid concentrations. A complex formulation like that covers all possible and desired aesthetic clinical facial treatment. The results of THJAMA' Filtrare amazing!!!! Long lasting at the injected site Great hydrophilic capacity Mouldability at surgical site Stabiliti post-operation

FACIAL FILLERS

THJAMA' Filleris a special line of dermal fillers based on monophasic cross-linked and non-cross linked hyaluronic acid. A range with 7 different products, 2 different technologies (TRIO and Dual Link), all CE certified by an international reputable Notify Body from Italy, used to create and restore all desired aesthetic facial outcomes.
THE NEXT GENERATION Skinboosters Standard skinboosters are simply non-cross linked HA, which hydrates the skin with short action time. Our dynamic 2nd generation skinbooster is a real pioneer in bringing the concept of skinboosters to the next level. The secret is a big touch of cross-linked hyaluronic acid for the long-lasting result combined with linear hyaluronic acid for the immediate effect to increase the moisturizing factor even further.
IMMEDIATE AND LONG-LASTING Dual-Link Technology The Dual-Link Technology combines the advantages of both linear HA and cross-linked HA in one unique line of products. The special formulation provides an immediate hydration effect, thanks to the linear HA, as well as a long-lasting result due to the cross-linking HA, ensuring patient satisfaction even further. It can be easily shaped for superficial treatments (THJAMA' FillerGlips) and easier to inject for deep treatments (THJAMA' FillerMax) as well.

FACE FILLERS

We offer a line of CE certified hyaluronic acid facial fillers with different products designed for specific and personalised goals.
With their different concentrations of hyaluronic acids and innovative cross-linked hyaluronic acid formula, our fully resorbable and long-lasting products allow multiple goals to be achieved depending on each patient's needs.
Latest generation fillers
We offer a wide range of face fillers. Thanks to the latest generation cross-linked hyaluronic acid, they satisfy every type of need for a specific and personalised goal. Easy to apply and fully resorbable: our filler private label represent a cutting-edge technology in dermal fillers sector.

5 KEY STRENGTHS

EXTRUDABILITY FROM THE SYRINGE FAVOURED BY THE VISCOUS-ELASTIC CHARACTERISTICS OF THE GEL,THE ERGONOMICS OF THE SYRINGE

GEL DISTRIBUTIONINTHE TISSUES ACHIEVED BY CONTROLLING THE COHESIVITY OF THE GELDEPENDING ON THE CONCENTRATION AND DEGREE OF CROSS-LINKING.

ABILITY TO RESPOND TOTISSUE STRESS (COMPRESSION ETC.) OVERTIME

PLASTIC BEHAVIOUR OFTHE GEL TO MATCH THE DYNAMICS OF THE FACE AND ITS EXPRESSIONS

NATURAL BIODEGRADATION OF THE PRODUCT TO ENSURE MAXIMUM SAFETY AND SECURITY OVER TIME

Monophasic: no particle sizedata avaialble
Ha molecular weight: 1-1.5 M Da
Osmolatility: 300 mOsm/Kg
Needles: Soft>30G, Medium/Strong >27G, Extra Strong >25G

EXTRUDABILITY FROM THE SYRINGE FAVOURED BY THE VISCOUS-ELASTIC CHARACTERISTICS OF THE GEL,THE ERGONOMICS OF THE SYRINGE

The process developed by THJAMA' LAB makes possible to obtain products characterised by dynamic viscosity that can be modulated according to the degree of crosslinking, concentration and molecular weight of the hyaluronic acid.

The M.M.A (macroMolecularAlignment) technology exploits the combination of heat and a direct mechanical extrusion step during the production phase, which is able to align the cross-linked hyaluronic acid molecules. This facilitates the extrusion of the gel from the syringe without compromising the dynamic viscosity of the product.

GEL DISTRIBUTION IN THE TISSUES ACHIEVED BY CONTROLLING THE COHESIVITY* OF THE GEL DEPENDING ON THE CONCENTRATION AND DEGREE OF CROSS-LINKING

The low cohesivity of the Soft product guarantees a high distribution of the product especially in the upper layers of the dermis, favouring its ability to perform a hydrating action on the tissues. On the contrary, Strong and Extrastrong fillers exhibit a high cohesivity, ideal to perform a filling and volumizing action.

*Zerbinati N. Et al, Polymers 2021;13:948
**Sundaram H et al. Plastic And Reconstr. Surgery. 2015; 136(4):678

ABILITY TO RESPOND TO TISSUE STRESS (COMPRESSION ETC.) OVER TIME

The elastic modulus (G') greater than 150 Pas of products such as Strong and Extrastrong guarantees a high mechanical response to transverse (parallel tissue movements) and perpendicular stresses (skin projection)

*Determinata a 0.1 Hz
**Falcone et al. J. Of Biomedical Mat. Res, 2008; 264:71

PLASTIC BEHAVIOUR OF THE GEL TO MATCH THE DYNAMICS OF THE FACE AND ITS EXPRESSIONS

The percentage of elasticity of OPERA fillers guarantees the products' ability to match the dynamics of facial expressions, thanks to the plastic and volumetric role played by facial fillers.

The M.F.HA (Micro-fragmentation HA) technology reduces the size of the cross-linked gel particles to the size of afew millimetres, favouring better hydration, a higher degree of swelling and a favourable ratio between elastic and viscous modulus over a wide stress range.

NATURAL BIODEGRADATION OF THE PRODUCT TO ENSURE MAXIMUM SAFETY AND SECURITY OVER TIME.

Fillers consist of only Pharma grade biotechnological hyaluronicacid. The absence of contaminants and by-products linked to the process guarantees the high safety and security of the product during use and in the biodegradation phase,induced exclusively by the presence of hyaluronidases that fragment the biopolymer, ensuring the metabolic pathway*

*ZhongS.P.etal. Biomaterials. 1994; 15(5):359

VISO

DERMAL FILLER SOFT

Fine Lines General Hydration

Filler Soft is recommended for situations where the area to be treated requires the elimination of fine wrinkles with a slight increase of volume and super hydration. Excellent choice of prevention and for delaying the formation of wrinkles, and for a hydrated healthier appearance

OTHER CHARACTERISTICS

Recommended areas: Periorbital (tear troughs), perioral and lips

TREATMENT AREA

Barcode Scars from acne Periocular wrinkles
Low viscosity and superficial injection possibilities enable to enhance the results of various treatments with its long-lasting moisturizing effect

COMPOSITION

INGREDIENTS CAS NUMBER FUNCTION % (g/100ml)
Water for injections 7732-18-5 Solvent 96.82
Sodium Hyaluronate 9067-32-7 Active ingredient: filling and moisturizing agent 2.0
BDDE 2425-79-8 Cross-linker 0.18
Sodium Hydroxide 1310-73-2 Buffering agent 0.30
Hydrochloric acid (37%) 7647-01-0 Buffering agent 0.63
Phosphoric acid (85%) 7664-38-2 Buffering agent 0.07

FINISHED PRODUCT SPECIFICATION

PARAMETERS STANDARD VALUES METHOD
Physical Aspect Gel Visual
Colour Colorless Visual
PH 6,5 ± 1 CH01 (pH meter)
BDDE residue < 2 ppm GC - MS
Hyaluronate title ≥2,0% UV-VISIBLE
Sterility test Sterile ISO 11737-2
Bacterial Endotoxin Detection ≤ 0,50 EU/ml EP 2.6.14, USP 85
Volume Control 1g± 5% CH03 (analytical balance)
Document owned by LIVS HEALTH CARE S.r.l. THJAMA' Brand Reproduction and dissemination without specific written authorization is prohibited

DERMAL FILLER MEDIUM

Moderate Volume Energetic Hydration

Thanks to its universal application properties, Filler Medium has become one of the most popular products from the THJAMA' Filler product portfolio. It can be used perfectly if our goal is to achieve medium volume and energetic hydration in the treated area.

OTHER CHARACTERISTICS

Recommended areas: nasolabial wrinkles, mentolabial (marionette wrinkles), glabella and lip volume increase

TREATMENT AREA

Nose
Tear trough
Lips
Temples
Medium deep grooves
Medium superficial grooves
This dermal filler is able to correct medium-superficial wrinkles

COMPOSITION

INGREDIENTS CAS NUMBER FUNCTION % (g/100ml)
Water for injections 7732-18-5 Solvent 96.66
Sodium Hyaluronate 9067-32-7 Active ingredient: filling and moisturizing agent 2.0
BDDE 2425-79-8 Cross-linker 0.19
Sodium Hydroxide 1310-73-2 Buffering agent 0.31
Hydrochloric acid (37%) 7647-01-0 Buffering agent 0.67
Phosphoric acid (85%) 7664-38-2 Buffering agent 0.07

FINISHED PRODUCT SPECIFICATION

PARAMETERS STANDARD VALUES METHOD
Physical Aspect Gel Visual
Colour Colorless Visual
PH 6,5 ± 1 CH01 (pH meter)
BDDE residue < 2 ppm GC - MS
Hyaluronate title ≥2,0% UV-VISIBLE
Sterility test Sterile ISO 11737-2
Bacterial Endotoxin Detection ≤ 0,50 EU/ml EP 2.6.14, USP 85
Volume Control 1g± 5% CH03 (analytical balance)
Document owned by LIVS HEALTH CARE S.r.l. THJAMA' Brand Reproduction and dissemination without specific written authorization is prohibited

DERMAL FILLER STRONG

Innovative High-Volume

My Filler Strong's high HA concentration makes it outstanding in the world of hyaluronic acid fillers. Recommended especially for contouring and high-volume corrections.

OTHER CHARACTERISTICS

Recommended areas: Cheek, chin, jawline, nose and midface

TREATMENT AREA

Naso-genal grooves
Marionette wrinkles
Mandibular edge
Deep wrinkles
Lips
Deep grooves
This dermal filler is able to correct deep wrinkles and smile lines.

COMPOSITION

INGREDIENTS CAS NUMBER FUNCTION % (g/100ml)
Water for injections 7732-18-5 Solvent 96.19
Sodium Hyaluronate 9067-32-7 Active ingredient: filling and moisturizing agent 2.40
BDDE 2425-79-8 Cross-linker 0.21
Sodium Hydroxide 1310-73-2 Buffering agent 0.36
Hydrochloric acid (37%) 7647-01-0 Buffering agent 0.76
Phosphoric acid (85%) 7664-38-2 Buffering agent 0.08

FINISHED PRODUCT SPECIFICATION

PARAMETERS STANDARD VALUES METHOD
Physical Aspect Gel Visual
Colour Colorless Visual
PH 6,5 ± 1 CH01 (pH meter)
BDDE residue < 2 ppm GC - MS
Hyaluronate title ≥2,0% UV-VISIBLE
Sterility test Sterile ISO 11737-2
Bacterial Endotoxin Detection ≤ 0,50 EU/ml EP 2.6.14, USP 85
Volume Control 1g± 5% CH03 (analytical balance)
Document owned by LIVS HEALTH CARE S.r.l. THJAMA' Brand Reproduction and dissemination without specific written authorization is prohibited

DERMAL FILLER EXTRA STRONG

Unique Solution Maximized volume

My Filler Max gives maximum volume with the immediate shining of the skin. With its high HA concentration can be an excellent choice for deep-volume correction..

OTHER CHARACTERISTICS

Recommended areas: cheeks, chin, jaw, nose and midface area.

FOR MEN

A more masculine appearance can be achieved with a strong and well-defi ned jawline, shape and volume

FOR WOMEN

Can be good for a strong volume correction with immediat shining effect

TREATMENT AREA

Naso-genal grooves
Marionette wrinkles
Mandibular edge
Deep wrinkles
Lips
Deep grooves
This dermal filler is able to correct deep wrinkles and particularly marked signs of aging.

COMPOSITION

INGREDIENTS CAS NUMBER FUNCTION % (g/100ml)
Water for injections 7732-18-5 Solvent 95.87
Sodium Hyaluronate 9067-32-7 Active ingredient: filling and moisturizing agent 2.60
BDDE 2425-79-8 Cross-linker 0.23
Sodium Hydroxide 1310-73-2 Buffering agent 0.39
Hydrochloric acid (37%) 7647-01-0 Buffering agent 0.82
Phosphoric acid (85%) 7664-38-2 Buffering agent 0.09

FINISHED PRODUCT SPECIFICATION

PARAMETERS STANDARD VALUES METHOD
Physical Aspect Gel Visual
Colour Colorless Visual
PH 6,5 ± 1 CH01 (pH meter)
BDDE residue < 2 ppm GC - MS
Hyaluronate title ≥2,0% UV-VISIBLE
Sterility test Sterile ISO 11737-2
Bacterial Endotoxin Detection ≤ 0,50 EU/ml EP 2.6.14, USP 85
Volume Control 1g± 5% CH03 (analytical balance)
Document owned by LIVS HEALTH CARE S.r.l. THJAMA' Brand Reproduction and dissemination without specific written authorization is prohibited

BODY

BODY FILLER

Our revolutionary macromolecular advanced hyaluronic acid body filler 100% Made in Italy. It remodels the body in a totally safe way without surgery. It allows to harmonize the large volumes of the body such as glutes, calves, forearms and areas where a natural redefinition of the body silhouette is necessary.

Last generation body filler production

The doctor can count on a safe, quality and easy to use product.
During the production and packaging process we carry out numerous verification tests on all the fillers produced, guaranteeing the total purity and efficency of the injectable product and the sterility of its packaging.

Thanks to the special formulation, it ensures optimal hydration and reinvigoration of muscle and tissues for a perfect reshaping.

Already after the first application your silhouette will appear more compact and outlined. Moreover, unlike most other invasive treatment, this body filler needs less time before resuming normal activities


TREATMENT AREA

Glutes
Calfs
Body depression
Arms

“MADE IN ITALY” FILLER INNOVATION

Our innovative body filler is designed for harmonising large body volumes such as buttocks, calves and forearms and areas requiring natural reshaping. A rapid, safe and non invasive treatment, a revolution that attracts ever more interest by women and men seeking a quick and painless solution to give new nourishment and tone to their body.

COMPOSITION

INGREDIENTS CAS NUMBER FUNCTION % (g/100ml)
Water for injections 7732-18-5 Solvent 96.82
Sodium Hyaluronate 9067-32-7 Active ingredient: filling and moisturizing agent 2.0
BDDE 2425-79-8 Cross-linker 0.18
Sodium Hydroxide 1310-73-2 Buffering agent 0.30
Hydrochloric acid (37%) 7647-01-0 Buffering agent 0.30
Phosphoric acid (85%) 7664-38-2 Buffering agent 0.07

FINISHED PRODUCT SPECIFICATION

PARAMETERS STANDARD VALUES METHOD
Physical Aspect Gel Visual
Colour Colorless Visual
PH 6,5 ± 1 CH01 (pH meter)
BDDE residue < 2 ppm GC - MS
Hyaluronate title ≥2,0% UV-VISIBLE
Sterility test Sterile ISO 11737-2
Bacterial Endotoxin Detection ≤ 0,50 EU/ml EP 2.6.14, USP 85
Volume Control 1g± 5% CH03 (analytical balance)
Document owned by LIVS HEALTH CARE S.r.l. THJAMA' Brand Reproduction and dissemination without specific written authorization is prohibited

CERTIFIED FILLER'S RESULTS

All our fillers are class III medical devices. In order to achieve the best possible clinical results, all formulations are developed with a focus on individual application purposes by using a combination of hyaluronic acids of different molecular weights in order to obtain different visco-elastic properties. These products have been developed to reshape tissues, noticeably reducing skin laxity, and to restore the skin's natural appearance by replenishing it with moisture, tone and radiance.

BIOREVITALIZING PRODUCT

The biorevitalizing fillers act on skin aging, especially of the face and neck, characterized by cellular depletion with relative reduction of tone and formation of wrinkles. They allow a rapid rejuvenation of the dermis and an immediate skin toning. This filler is ideal for the correction of minor facial skin depressions. It prevents and acts on photo aging and chrono aging damages.

Other characteristics
low viscosity in a syringe of 2 ml

Extra characteristic
excellent for décolleté and neck rejuvenation as well


THE RESULT

Ahydrated, radiant-looking
and even-textured
complexion, that lasts longer
with increased effectiveness
and a double dose.


COMPOSITION

INGREDIENTS CAS NUMBER FUNCTION % (g/100ml)
Water for injections 7732-18-5 Solvent 96.91
Sodium Hyaluronate 9067-32-7 Active ingredient: filling and moisturizing agent 2.0
BDDE 2425-79-8 Cross-linker 0.09
Sodium Hydroxide 1310-73-2 Buffering agent 0.30
Hydrochloric acid (37%) 7647-01-0 Buffering agent 0.63
Phosphoric acid (85%) 7664-38-2 Buffering agent 0.07

FINISHED PRODUCT SPECIFICATION

PARAMETERS STANDARD VALUES METHOD
Physical Aspect Gel Visual
Colour Colorless Visual
PH 6,5 ± 1 CH01 (pH meter)
BDDE residue < 2 ppm GC - MS
Hyaluronate title ≥2,0% UV-VISIBLE
Sterility test Sterile ISO 11737-2
Bacterial Endotoxin Detection ≤ 0,50 EU/ml EP 2.6.14, USP 85
Volume Control 1g± 5% CH03 (analytical balance)
Document owned by LIVS HEALTH CARE S.r.l. THJAMA' Brand Reproduction and dissemination without specific written authorization is prohibited